The effect of vitamin D3 on the symptoms of patients with irritable bowel syndrome

The Effect of Vitamin D3 on Quality of Life and Symptoms of patients with Irritable Bowel Syndrome and vitamin D3 Deficiency

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180617040114N4

Enrollment

Registered

2020-12-16

Start date

2020-04-26

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with irritable bowel syndrome. Irritable bowel syndrome

Interventions

Intervention group: Patients in this study are given an intramuscular injection of vitamin D. Its dose is 300,000 units. After 4 weeks of injection, patients' quality of life and the degree of gastroi

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Vitamin D levels between 15-30 ng/ml Absence of any gastrointestinal surgery Lack of severe mental and behavioral disorders Patients with irritable bowel syndrome according to the diagnosis of a gastroenterologist according to ROME-III criteria

Exclusion criteria

Exclusion criteria: Consumption a vitamin D supplement one year before enrollment. Consumption of nicotine and its derivatives in the last 6 months

Design outcomes

Primary

Measure	Time frame
Degree of gastrointestinal symptoms and irritable bowel syndrome. Timepoint: It is measured one day before the intervention and 4 weeks after the intervention. Method of measurement: Using Extra-intestinal symptoms severity scale questionnaire.;Quality of life in patients with irritable bowel syndrome. Timepoint: It is measured one day before the intervention and 4 weeks after the intervention. Method of measurement: Using a quality of life questionnaire for patients with irritable bowel syndrome.	—

Measure

Time frame

Degree of gastrointestinal symptoms and irritable bowel syndrome. Timepoint: It is measured one day before the intervention and 4 weeks after the intervention. Method of measurement: Using Extra-intestinal symptoms severity scale questionnaire.;Quality of life in patients with irritable bowel syndrome. Timepoint: It is measured one day before the intervention and 4 weeks after the intervention. Method of measurement: Using a quality of life questionnaire for patients with irritable bowel syndrome.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Savarsfly

Arak University of Medical Sciences

Leila.saavar@gmail.com+98 86 3417 3601

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026