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Evaluation of the Effect of Melissa Officinalis L ( Lemon Balm) Capsule on Cognitive Impairment in Depressed Patients Treated With ECT

Evaluation of the Effect of Melissa Officinalis L ( Lemon Balm) Capsule on Cognitive Impairment in Depressed Patients Treated With ECT

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180613040083N1
Enrollment
80
Registered
2022-06-10
Start date
2022-10-22
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depression , ECT. Mental disorder, Not Otherwise Specified

Interventions

Intervention 1: Intervention group: 40 depressed patients treated with ECT, receiving 500mg lemon balm capsules (made by the Made by a pharmacologist) every 8 hours after a month Evaluation with ques

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The age range of patients is 18-65 years. Their Major Depressive Disorder has been confirmed by a psychiatrist The patient has no history of allergy to The mint family. Lack of physical illness leading to Cognitive Impairment such as Head Trauma, Dementia, Retardation - Mental Retardation And EpilepsyPatients Receiving SSRIs (according to a psychiatrist).

Exclusion criteria

Exclusion criteria: Patients who have other Mental Misorders in addition to Depression.. Reluctance to continue cooperation before The end of the project Occurrence of stressful events affecting The patient's mood during the implementation of The plan Use of other Antidepressants Drugs(except SSRIs)

Design outcomes

Primary

MeasureTime frame
Cognitive Disorders Score in Cognitive Status Assessment Questionnaire (MMSE Questionnaire). Timepoint: Measurement of Cognitive Disorders before intervention and one month after consumption of Lemon Balm Capsules. Method of measurement: Cognitive Status Assessment Questionnaire (MMSE Questionnaire).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Massoud Nikfarjam

Shahre-kord University of Medical Sciences

Nikmas140@gmail.com+98 38 3333 0061

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026