The effect of exercise and royal jelly on inflammatory factors in multiple sclerosis patients

Effect of 6 weeks aerobic exercise and oral Royal Jelly on TNF-alpha, hs-CRP and neutrophil in multiple sclerosis patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180612040073N2

Enrollment

Registered

2018-11-30

Start date

2018-11-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis. Multiple sclerosis

Interventions

Intervention 1: First intervention group: Exercise and Royal jelly Name of the used sub

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Multiple sclerosis patients: Expanded Disability Status Scale (EDSS) between 0-4 Lack of any supplement Lack of cardiovascular disease

Exclusion criteria

Exclusion criteria: Multiple sclerosis patients: EDSS more than 4 Use of pharmaceutical supplements With cardiovascular disease

Design outcomes

Primary

Measure	Time frame
Tumor necrosis factor alpha changes. Timepoint: Blood sampling at the beginning of the study (24 hours before the intervention) and 24 hours after the last session of the research protocol. Method of measurement: "Tumor necrosis factor alpha" test kit.;High-sensitivity C-reactive Protein Changes. Timepoint: Blood sampling at the beginning of the study (24 hours before the intervention) and 24 hours after the last session of the research protocol. Method of measurement: "High-sensitivity C-reactive Protein" test kit.;Neutrophils counts. Timepoint: Blood sampling at the beginning of the study (24 hours before the intervention) and 24 hours after the last session of the research protocol. Method of measurement: Automatic cell counting machine.	—

Measure

Time frame

Tumor necrosis factor alpha changes. Timepoint: Blood sampling at the beginning of the study (24 hours before the intervention) and 24 hours after the last session of the research protocol. Method of measurement: "Tumor necrosis factor alpha" test kit.;High-sensitivity C-reactive Protein Changes. Timepoint: Blood sampling at the beginning of the study (24 hours before the intervention) and 24 hours after the last session of the research protocol. Method of measurement: "High-sensitivity C-reactive Protein" test kit.;Neutrophils counts. Timepoint: Blood sampling at the beginning of the study (24 hours before the intervention) and 24 hours after the last session of the research protocol. Method of measurement: Automatic cell counting machine.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Vahidian-Rezazadeh

University of Sistan and Baluchestan

vahidian@ped.usb.ac.ir+98 54 3341 6107

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026