Effect of probiotic on treatment of bacterial vaginitis and preservation of vaginal bacterial flora in patients treated with metronidazole

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180612040071N2

Enrollment

128

Registered

2020-01-03

Start date

2019-11-26

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bacterial vaginosis. Inflammatory diseases of female pelvic organs

Interventions

Intervention 1: Intervention group: Patients are treated with metronidazole orally twice daily (morning and night) for 7 days and then treated with probiotic suppository every 3 days for 3 weeks. Inte

Eligibility

Sex/Gender

Female

Age

18 Years to 48 Years

Inclusion criteria

Inclusion criteria: Women with bacterial vaginitis according to the Amsel criteria married 18-48 years old

Exclusion criteria

Exclusion criteria: People with immunodeficiency disease and HIV People with genital and urinary tract infections Antibiotic users within two weeks prior to inclusion Patients with candidiasis vaginitis Menopause Pregnant women or during lactation Patients who do not allow pelvic examination

Design outcomes

Primary

Measure	Time frame
Bacterial vaginitis symptoms. Timepoint: 1 month (30dayes ) after the use of probiotics or placebo. Method of measurement: questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Nazeri

Kashan University of Medical Sciences

nazeri_me@kaums.ac.ir+98 31 5554 1112

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026