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Investigating the effectiveness of repetitive brain magnetic stimulation (rTMS) on the level of anxiety, depression, sleep and quality of life in patients with HIV and treatment-resistant depression

Investigating the effectiveness of repetitive brain magnetic stimulation (rTMS) on the level of anxiety, depression, sleep and quality of life in patients with HIV and treatment-resistant depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180610040037N4
Enrollment
30
Registered
2023-05-31
Start date
2023-04-08
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human immunodeficiency virus. Human immunodeficiency virus [HIV] disease

Interventions

Intervention 1: Intervention group: They receive rTMS protocol in addition to routine treatment. The research was conducted in such a way that the subjects will be assessed by the Beck depression test

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Insomnia and depression Ability to participate in therapy sessions At least diploma education age between 20 and 65 years Stay in Tehran Full consciousness and able to speak Persian Physical and mental preparation is necessary to answer the questions not having a specific mental illness before treatment (based on the patient's report)

Exclusion criteria

Exclusion criteria: Subject's unwillingness to participate or continue participating in research Getting malignancies Having autoimmune disorders Facing specific psychological crises during the stages of work Doing other psychological treatments Need to be re-hospitalized Seizures

Design outcomes

Primary

MeasureTime frame
Anxiety and depression level. Timepoint: One week before the treatment and in the 5th and 10th weeks after the treatment and if the treatment continues until the 20th week. Method of measurement: To check depression, the Hamilton Depression Rating Scale (HDRS) questionnaire and its severity are also checked and recorded using the Beck depression measuring tool.;The quality of life. Timepoint: The mentioned form will be completed one week before the treatment and in the 5th and 10th weeks after the treatment and if the treatment continues until the 20th week. Method of measurement: by the sf 36 quality of life questionnaire, which has been confirmed in various Persian and English studies in terms of validity and reliability.;Sleep quality questionnaire score. Timepoint: The mentioned form will be completed one week before the treatment and in the 5th and 10th weeks after the treatment and if the treatment continues until the 20th week. Method of measurement: by the sleep quality questionnaire, which has been confirmed in various Persian and English studies in terms of validity and reliability.

Secondary

MeasureTime frame
CD3 and CD4 levels. Timepoint: before and 3 months after receiving repetitive brain magnetic stimulation (rTMS) treatment. Method of measurement: routine blood sample Test for surface counting CD3-CD4.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Ali Dehghan Manshadi

Tehran University of Medical Sciences

a_dehghanm@sina.tums.ac.ir+98 21 6658 1583

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026