Skip to content

Adverse effects and Efficacy of IFN-? (Gamarek™) among Sepsis Patients in Imam Khomeini Hospital Complex, Tehran., A Clinical Trial Study Phase ?

Adverse effects and Efficacy of IFN-? (Gamarek™) among Sepsis Patients in Imam Khomeini Hospital Complex, Tehran., A Clinical Trial Study Phase ?

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180610040037N3
Enrollment
120
Registered
2023-02-13
Start date
2023-03-06
Completion date
Unknown
Last updated
2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis. Urinary tract infection

Interventions

Intervention 1: Intervention group: Patients who take interferon gamma-1b (Gammarec) daily with standard treatment for 5 days. Intervention 2: Control group: Patients who take only standard treatment.

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age 18 to 75 years Patients who have legally accepted using the medicine Patients that hospitalized in ICU or wards under special supervision with diagnosis of septic shock or severe sepsis, sepsis and critical illness

Exclusion criteria

Exclusion criteria: during pregnancy and breastfeeding Simultaneous use with Deferiprone Hypersensitivity to interferon gamma 1-b (Gammarec) medicine

Design outcomes

Primary

MeasureTime frame
Effect of the gamma interferon medicine (Gammarec) using on sepsis patients. Timepoint: from the beginning of taking the medicine for 5 days. Method of measurement: Based on physicians and nurses reports and clinical and laboratory observations.

Secondary

MeasureTime frame
The frequency of death due to the sepsis;. Timepoint: from the beginning of taking the medicine for 5 days. Method of measurement: based on patient clinical report.;Number of people discharged from ICU after treatment by Gammarec. Timepoint: from the beginning of taking the medicine for 5 days. Method of measurement: Based on physicians and nurses reports and clinical and laboratory observations.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Ali Dehghan Manshadi

Tehran University of Medical Sciences

a_dehghanm@sina.tums.ac.ir+98 21 6658 1583

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026