Effect of Clofibrate in term neonatal jaundice

Comparing the effect of phototherapy plus different doses of Clofibrate in level of bilirubin in term newborns with non- hemolytic Icter

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180610040036N1

Enrollment

Registered

2018-12-28

Start date

2017-05-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal jaundice. Neonatal jaundice, unspecified

Interventions

Intervention 1: Intervention group 1: Clofibrate 50 mg/kg (Clofibrate of ALHAVI made in Iran , Oral single dose before phototherapy). Intervention 2: Intervention group 2: Clofibrate 50 mg/kg (Cofi

Eligibility

Sex/Gender

All

Age

2 Days to 14 Days

Inclusion criteria

Inclusion criteria: Term neonates(gestational age more than 38 weeks) Iranian,Asian race 2-14 day-old Non-hemolytic icter Total serum bilirubin(TSB)=13-20 mg/dl

Exclusion criteria

Exclusion criteria: Hemolytic icter Total serum bilirubin(TSB) >20 mg/dl Sepsis

Design outcomes

Primary

Measure	Time frame
Total serum bilirubin level. Timepoint: Total serum bilirubin level before intervention then 6,12,24,48,72 hours after intervention. Method of measurement: Mindray BS-200 analyzer.	—

Secondary

Measure	Time frame
Cholesterol. Timepoint: At bedtime before intervention , 72 hours after intervention. Method of measurement: Mindray BS-200 analyzer.;Triglycerides. Timepoint: At bedtime before intervention , 72 hours after intervention. Method of measurement: Mindray BS-200 analyzer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNarges Gholami

Shahid Beheshti University of Medical Sciences

nargesgholami@sbmu.ac.ir+98 21 5102 5182

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026