Pain control with intravenous Morphine versus Fentanyl in adult traumatic patients

Comparing the analgesic response of intravenous Morphine versus Fentanyl for adult traumatic patients in emergency department

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180608040013N1

Enrollment

180

Registered

2019-07-17

Start date

2018-06-22

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult traumatic patients.

Interventions

Intervention 1: Intervention group: A single dose of intravenous morphine (0.1 mg/kg). Intervention 2: Control group: A single dose of intravenous fentanyl (5 µg/kg).

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who have an initial pain score of 4 or more (0 = no pain and 10 = worst possible pain) according to the Numerical Rating Scale (NRS) upon presentation. Age more than 18 years Initial oxygen saturation greater than 95% Patients with a GCS score of 15

Exclusion criteria

Exclusion criteria: Systolic blood pressure less than 90 mmHg Known pregnancy Patients with chronic pain syndromes (such as sickle cell disease or fibromyalgia) Cognitive impairment Known allergy to either fentanyl or morphine

Design outcomes

Primary

Measure	Time frame
Pain reduction based on the Numerical Rating Scale (NRS). Timepoint: At baseline, 5, 10, 30, 120 minutes post baseline. Method of measurement: Numerical Rating Scale (NRS).	—

Secondary

Measure	Time frame
Time to lowest pain score. Timepoint: From baseline to 2 hours post baseline. Method of measurement: Stopwatch.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNajmeh Zarei Jelyani

Shiraz University of Medical Sciences

n_zarei@sums.ac.ir+98 71 3630 2747

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026