The effect of basil extract in insomnia .

The comparison of the efficacy of hydroalcoholic extract of ocimum basilicum and placebo in treatment of insomnia in depressed patients who are referred to psychiatry clinic of Hafez hospital in Shiraz (a randomized double blind clinical trial)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180603039967N1

Enrollment

Registered

2018-11-04

Start date

2018-10-31

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major deprassion + Insomnia. Insomnia

Interventions

Intervention 1: Intervention group: Ocimum basilicum will be dried and hydroalcoholic extract will be prepared. Capsules will be filled with hydroalcoholic extract powder . The patients will recieve

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The patients betwwen 18 to 65 years old suffering from major deppresion Getting at least the score 12 out of 28 of the insomnia severity index questionnaire

Exclusion criteria

Exclusion criteria: Taking any sedative medication in last month Sufferng from significant medical diseases like cardiopulmonary failure, cancer, vascular disease, rheumatologic diseases, history of seizure, thyroid disease, ... Taking anticoagulant or antiplatelet medications like warfarin, aspirin ,... Opioid and alcohol addiction Pregnancy and lactation

Design outcomes

Primary

Measure	Time frame
Beck depression inventory score /Insomnia Severity Index score (ISI) / Pittsburgh Sleep Quality Index score(PSQI). Timepoint: Filling the questionnaires before starting the intervention and 4 week after taking drug. Method of measurement: Beck depression inventory /Insomnia Severity Index (ISI) / Pittsburgh Sleep Quality Index (PSQI).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Nazari

Shiraz University of Medical Sciences

culture@sums.ac.ir+98 71 3212 2464

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026