Comparison the effect of interathecal injection of pethidine versus bupivacaine on hemodynamics

Comparison the effect of interathecal injection of pethidine versus bupivacaine on hemodynamics in hip surgery.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180603039966N1

Enrollment

Registered

2018-08-31

Start date

2018-07-23

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fractures of the hip and femor.

Interventions

Intervention 1: Intervention group1: patients with hip or femor fractures, who are candidates for surgery, are going to be anesthetized by intrathechal injection of 1 mg/kg Pethidine(Aburaihan pharmac

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with hip or femoral fractures

Exclusion criteria

Exclusion criteria: Allergy to Local Anesthetics and Pethidine Coagulation Disorders Patients refusal inability to maintain position during needle puncture localized sepsis of the puncture site High Intra Cranial Pressure

Design outcomes

Primary

Measure	Time frame
Heart Rate per minute. Timepoint: Heart rate per minute, will be recorded on minutes 0, 3, 6, 9, 12, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 90 and every 30 minute after that. Method of measurement: vital signs will be measured by Saadat (Alborz B9) patient's monitoring device.;Mean Arterial Pressure(MAP). Timepoint: Mean Arterial Pressure(MAP), will be recorded on minutes 0, 3, 6, 9, 12, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 90 and every 30 minute after that. Method of measurement: vital signs will be measured by Saadat (Alborz B9) patient's monitoring device.;Systolic Blood Pressure. Timepoint: Systolic Blood Pressure, will be recorded on minutes 0, 3, 6, 9, 12, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 90 and every 30 minute after that. Method of measurement: vital signs will be measured by Saadat (Alborz B9) patient's monitoring device.;Diastolic Blood Pressure. Timepoint: Diastolic Blood Pressure, will be recorded on minutes 0, 3, 6, 9, 12, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 90 and every 30 minute after that. Method of measurement: vital signs will be measured by Saadat(Alborz B9) patient's monitoring device.	—

Measure

Time frame

Heart Rate per minute. Timepoint: Heart rate per minute, will be recorded on minutes 0, 3, 6, 9, 12, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 90 and every 30 minute after that. Method of measurement: vital signs will be measured by Saadat (Alborz B9) patient's monitoring device.;Mean Arterial Pressure(MAP). Timepoint: Mean Arterial Pressure(MAP), will be recorded on minutes 0, 3, 6, 9, 12, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 90 and every 30 minute after that. Method of measurement: vital signs will be measured by Saadat (Alborz B9) patient's monitoring device.;Systolic Blood Pressure. Timepoint: Systolic Blood Pressure, will be recorded on minutes 0, 3, 6, 9, 12, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 90 and every 30 minute after that. Method of measurement: vital signs will be measured by Saadat (Alborz B9) patient's monitoring device.;Diastolic Blood Pressure. Timepoint: Diastolic Blood Pressure, will be recorded on minutes 0, 3, 6, 9, 12, 15, 20, 25, 30, 35, 40, 45, 50, 55, 60, 75, 90 and every 30 minute after that. Method of measurement: vital signs will be measured by Saadat(Alborz B9) patient's monitoring device.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBabak Mojaver Aghili

Gorgan University of Medical Sciences

Dr.mojaveraghili@goums.ac.ir+98 17 3222 0561

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026