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Effect of acetazolamide and paracetamol on referral pain after surgery

Comparison of the effect of acetazolamide and paracetamol on referral pains following laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180603039958N1
Enrollment
114
Registered
2019-01-24
Start date
2009-03-21
Completion date
Unknown
Last updated
2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

referred postoperative painafter laparoscopic cholecystectomy. Acquired total absence of pancreas

Interventions

Intervention 1: The first group (acetazolamide group) received acetazolamide tablets 250 mg half an hour before induction of anesthesia plus 20 cc water + placebo administration Paracetamol (isotonic

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: All patients undergoing laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Having a disease that causes pain in the sensation Receiving analgesic and anti-inflammatory drugs within 48-48 hours Drug addicts Contraindications for acetaminophen, acetazolamide, lactose and starch (used in placebo) The presence of inflammation based on surgical surgeries in a way that overlaps adhesions and dyslexia is more likely to last longer than an hour. Patients Needed Dren

Design outcomes

Primary

MeasureTime frame
Pain in cholecystectomy surgery by laparoscopy due to uncomplicated. Timepoint: Immediately before surgery, after surgery and after awakening, discharge from the recovery, the day after surgery, and upon discharge from the hospital. Method of measurement: Questionnaire based on purpose and patient view.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Rajaee

Mashhad University of Medical Sciences

nrc@mums.ac.ir+98 51 3802 2677

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026