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Comparsion of the effect of dexmedetomidine with morphine in surgeries under epidural anesthesia

Comparsion of the effect of dexmedetomidine and bupivacaine with morphine and bupivacaine on block quality in leg fracture surgeries under epidural anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180602039954N1
Enrollment
80
Registered
2019-03-10
Start date
2018-01-21
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Leg fracture. Other fractures of lower leg

Interventions

Intervention 1: Intervention group1: consisted of patients who received 12 ml of 0.5% bupivacaine hydrochloride plus dexmedetomidine 1µg/kg (B+D). Intervention 2: Intervention group2: consisted of pat

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-60 years old with anesthesia risk ASA I, II

Exclusion criteria

Exclusion criteria: Lack of satisfaction with epidural blocking Patients dependent on any psychiatric drug Patients with localized infection at the site of the epidural block Patients who had an allergy to the study drugs. Patients with neurological and neuro-macular diseases and psychologists Patients with coagulation disorder Patients who require an analgesic drug during surgery. Patients who fail their epidural block and were under general anesthesia Pregnant women

Design outcomes

Primary

MeasureTime frame
Block Epidural Quality. Timepoint: Epidural block every two minutes until the sensory level reaches T12, then every 15 minutes; motion block every 5 minutes to bromage 3 times every 30 minutes; Sedation Score every 30 minutes; VAS Score every 30 minutes; Bp, HR; Sat O2 every 5 minutes to half an hour every 15 minutes. Method of measurement: Sensory block with cold swab; Motion block with Bromage scale; Postoperative pain using VAS score; Sedation using Ramsay Scale method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Gooshe

Ahvaz University of Medical Sciences

Goosheh-m@ajums.ac.ir+98 61 3311

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026