Skip to content

Flexible progestin primed ovarian stimulation in patients with polycystic ovarian syndrome

Comparison of pregnancy outcome between flexible progestin primed ovarian stimulation and gonadotropin releasing hormone GnRH antagonist protocol in patients with polycystic ovarian syndrome-Randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180528039878N2
Enrollment
200
Registered
2021-04-06
Start date
2021-06-22
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility associated with anovulation. Female infertility associated with anovulation

Interventions

Intervention 1: Intervention group: Ovarian stimulation starts on the third day of menstruation using gonadotropins (150 units). The dose of gonadotropins is adjusted based on each individual's ovaria

Sponsors

Mehr Medical Institute
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 41 Years

Inclusion criteria

Inclusion criteria: Age under 41 years At least two of the Rotterdam criteria (polycystic ovaries on ultrasound, hyperandrogenism, irregular menstrual cycle)

Exclusion criteria

Exclusion criteria: Moderate and sever endometriosis Medroxyprogesterone acetate contraindications Allergy to medroxyprogesterone acetate Sever male factor

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: Six weeks after embryo transfer. Method of measurement: Ultrasonography.;Ongoing pregnancy. Timepoint: Twelve weeks after embryo transfer. Method of measurement: Ultrasonography.;Ovarian hyperstimulation syndrome. Timepoint: The day of ovulation induction. Method of measurement: Clinical symptoms.

Secondary

MeasureTime frame
Total Gonadotropin dose. Timepoint: The day of triggering final oocyte maturation. Method of measurement: Total dose.;Duration of ovarian stimulation. Timepoint: The day of ovulation induction. Method of measurement: Number of days.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzieh Mehrafza

Mehr Medical Institute

marzieh.mehrafza@gmail.com+98 13 3376 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026