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Evaluation the effect of syrup made from sweet Almond in pediatric nocturnal cough

Evaluation of the effectiveness of a syrup made from sweet Almond in pediatric nocturnal cough with upper respiratory tract infection(common cold) compared to Diphenhydramine: A randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180527039867N1
Enrollment
60
Registered
2018-06-13
Start date
2018-08-23
Completion date
Unknown
Last updated
2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough due to upper respiratory tract infection(common cold). Acute nasopharyngitis [common cold]

Interventions

Intervention 1: Intervention group: The oral syrup from sweet almond (equivalent to the dose of Diphenhydramine syrup received in the control group: 1 mg/ kg ) will be prescribed in 1 Dose half an ho

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 12 Years

Inclusion criteria

Inclusion criteria: The patients's age is two to twelve years old Cough due to upper respiratory tract infection (common cold) for less than 7 days Concomitant symptoms (mild fever: less than 39 ° C, sore throat, cramps, rhinorrhea, mild headache, feeling tired, sneezing Do not use any anti-cough product 18 hours before the intervention Lack of underlying disease (asthma, allergic rhinitis, sinusitis, laryngo tracheobronchitis, congenital heart disease, chronic lung disease, diabetes, kidney disease) Conscious written consciously from parents to enter the study Possibility of patient Follow up

Exclusion criteria

Exclusion criteria: Children with signs and symptoms of asthma, pneumonia, allergic rhinitis, sinusitis, laryngo tracheobronchitis, congenital heart disease, chronic lung disease, diabetes, kidney disease The onset of symptoms of otitis, sinusitis, onset of symptoms of of the lower respiratory tract infection , the addition of a bacterial infection to the viral infection (edema, respiratory problem, severe sore throat with painful ingestion, nausea, vomiting, fever above 39 °, septic nasal discharge, Facial and peri orbital pain) during the intervention Lack of allergy (presence of symptoms such as i itchy eye & nose, a history of prolonged cold periods,history of repeating similar symptoms, positive family history of allergy, history of drug and food allergy), The presence of sign and symptoms of a Reactive Airway Disease including: tachypnea and tachycardia, short breath, chest tightness ) Getting any anti cough drug before intervention Not using or using irregularly recommended medications Add other cough drugs to treatment during the intervention allergic reaction to drug combinations during the study disrelish to cooperate until the end of the study Inaccessibility of the patient during the study

Design outcomes

Primary

MeasureTime frame
Cough frequency. Timepoint: At the beginning of the study, the first and second day of intervention. Method of measurement: Likert scale Checklist.;Cough severity. Timepoint: At the beginning of the study, the first and second day of intervention. Method of measurement: Likert scale Checklist.;Nightly sleep quality of the child. Timepoint: At the beginning of the study, the first and second day of intervention. Method of measurement: Likert scale Checklist.;Nightly sleep quality of the parent. Timepoint: At the beginning of the study, the first and second day of intervention. Method of measurement: Likert scale Checklist.

Secondary

MeasureTime frame
Time Control Signs. Timepoint: Any time during the study. Method of measurement: Report by the child's parents.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Karimi

Iran University of Medical Sciences

karimi.z@tak.iums.ac.ir+98 21 5558 0388

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026