Comparison of the effect of Quetiapine and Trazodone on sleep improvement

Comparing the effect of Trazodone and Quetiapine on recovery of sleep disturbances on patients who received methadone maintenance therapy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180527039860N1

Enrollment

Registered

2018-10-07

Start date

2018-08-06

Completion date

Unknown

Last updated

2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep disturbances. Disorders of initiating and maintaining sleep [insomnia]

Interventions

Intervention 1: "Intervention group 1": In male patients with methadone treatment that has been associated with sleep disturbances during treatment with this drug, terazodone tablet from Tehran Chem

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Patients undergoing Methadone maintenance treatment, who received a total score of over 5 according to the PSQI questionnaire The substance used by the individual does not interfere with Trazadone and Quetiapine drugs

Exclusion criteria

Exclusion criteria: Unwillingness to participate in the study Having a previous illness that prohibits prescribing drugs

Design outcomes

Primary

Measure	Time frame
Sleep quality. Timepoint: End of one month after treatment begins. Method of measurement: Pittsburgh sleep quality index.	—

Secondary

Measure	Time frame
General health. Timepoint: End of one month after treatment begins. Method of measurement: General health questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSekine Javadian

Babol University of Medical Sciences

Javadian1939@yahoo.com+98 11 3219 0181

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026