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Evaluation of the palliative effect of a topical emulgel containing piroxicam-entrapped nanoniosomes on patients suffering OA or RA with joint pain

Clinical trial of a topical emulgel containing piroxicam-entrapped nanoniosomes in patients with osteoarthritis or rheumatoid arthritis complaining joint pain

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180526039839N1
Enrollment
40
Registered
2024-03-16
Start date
2024-02-20
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Osteoarthritis. Condition 2: Rheumatoid arthritis. Osteoarthritis of knee Rheumatoid arthritis with rheumatoid factor

Interventions

Intervention 1: Control group: Patients receiving topical standard treatment including Razak Pharmaceutical Co. piroxicam 0.5% gel twice daily for one week. Intervention 2: Intervention group: Patient

Sponsors

Daroo Sazan Sorena Exir Company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Experiencing pain in one or more joint Having acute (less than three weeks), Sub-acute (three weeks to three months) or chronic (more than three months) joint pain Age between 18 to 80 years old

Exclusion criteria

Exclusion criteria: Consumption of oral, rectal, or parenteral pain killers or anti-inflammation drugs including corticosteroids, NSAIDs, acetaminophen, narcotics, Herbal pain killers with scientifically-proven effect

Design outcomes

Primary

MeasureTime frame
Joint pain in rest and during movement. Timepoint: The pain levels will be recorded daily from the first to the seventh day of initiating the clinical trial. Method of measurement: The pain level will be measured using numerical rating scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Amini

Shiraz University of Medical Sciences

Afshinaminie@gmail.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026