Effectiveness of transcranial direct current stimulation in treatment post-traumatic stress disorder

Comparison of the effectiveness of transcranial direct current stimulation (tDCS) and eye movement desensitization and reprocessing (EMDR) on post-traumatic stress disorder symptoms (PTSD)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180522039775N1

Enrollment

Registered

2018-10-20

Start date

2018-01-29

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic stress disorder (PTSD). Post-traumatic stress disorder (PTSD)

Interventions

Intervention 1: Intervention group 1: In this group, direct current stimulation was delivered from a battery-driven (Neurosoft, Russia), constant current stimulator and transferred by a pair of 5×7 (3

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age of 18 to 60 years Sign the informed consent form Post-traumatic stress disorder Having a PTSD checklist version (PCL-5) greater than 50 Experienced no change in psychosocial treatments for 2 months before tDCS Experienced no change in psychotropic medication

Exclusion criteria

Exclusion criteria: Axis 1 psychiatric disorders or personality disorders. A history of a significant neurological or medical disorder such as seizure, brain tumors, traumatic brain injury , stroke, Parkinson’s disease, dementia, Huntington’s chorea, multiple sclerosis Changed medications in the 8 weeks prior to commencement of the trial Implanted medication pumps of any sort that would increase the risk of tDCS The risk of Seizure with any reasons, high Intracranial pressure, The history of epilepsy or Seizure in the first relatives, any metal in Head, brain trauma, history of loss of consciousness for more than 5 minutes Pregnancy, breastfeeding High risk of Suicide

Design outcomes

Primary

Measure	Time frame
Score of PTSD on post-traumatic stress index (PCL-5). Timepoint: Before intervention, Final session, one month after intervention. Method of measurement: Post-traumatic stress index (PCL-5).	—

Secondary

Measure	Time frame
Score of anxiety. Timepoint: Before intervention, final session ,one month after intervention. Method of measurement: Beck Anxiety Inventory.;Score of depression. Timepoint: Before intervention, final session ,one month after intervention. Method of measurement: Beck Depression Inventory (BDI-II).;Score of rumination. Timepoint: Before intervention, final session ,one month after intervention. Method of measurement: Ruminative Response Scale (RRS).	—

Measure

Time frame

Score of anxiety. Timepoint: Before intervention, final session ,one month after intervention. Method of measurement: Beck Anxiety Inventory.;Score of depression. Timepoint: Before intervention, final session ,one month after intervention. Method of measurement: Beck Depression Inventory (BDI-II).;Score of rumination. Timepoint: Before intervention, final session ,one month after intervention. Method of measurement: Ruminative Response Scale (RRS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Rezaei

Bagheiat-allah University of Medical Sciences

Rezaee.mehdi15@yahoo.com+98 21 5675 9071

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026