Evaluation of the effect of SRP on levels of salivary biomarkers of mmp7 and mucin4 in patients with moderate to severe chronic Tissue Inflammation

Evaluation of the effect of non-invasive periodontal therapy(SRP) on levels of salivary biomarkers of mmp7 and mucin4 in patients with moderate to severe chronic periodontitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180521039761N1

Enrollment

Registered

2018-08-25

Start date

2018-05-22

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moderate to severe chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group: A group of patients for whom oral contraceptive practice (OHI) and oral administration of 2 ml of 10 ml of .2% chlorhexidine d-gluconate solution are administered f

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with moderate to severe periodontitis from 30 to 60 years of age

Exclusion criteria

Exclusion criteria: Pregnancy History of smoking and alcohol Chronic inflammatory diseases of the skin and oral mucosa Systemic diseases that affect periodontal conditions Periodontal acute diseases such as periodontal abscesses Radiographic evidence of visible bone resorption in posterior B.W

Design outcomes

Primary

Measure	Time frame
MUCIN4/MMP7. Timepoint: Before starting the study and one month later. Method of measurement: ELISA Kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNajmeh Shooraki

Boushehr University of Medical Sciences

N.shooraki@bpums.ac.ir+98 77 3332 2081

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026