Scar. Scar conditions and fibrosis of skin
Conditions
Interventions
Intervention 1: Intervention group: After transferring the mesh to the receptor area, the "Meshfill" gel is applied to the receptor regions by a syringe attached to a flexible catheter (size 14-16). A
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-50 years old. Having 20-50 percent of thermal burn. Having two burned areas that are almost identical in terms of location and depth. Willing to cooperate and follow up on treatment and complete the informed consent form.
Exclusion criteria
Exclusion criteria: Patients who are pregnant or breastfeed. Burn in joints, face, perineum and hands. Having concomitant diseases (diabetes, connective tissue disease, chronic kidney disease, cardiovascular disease) and any type of disease that impairs the immune system and delays wound healing. Suffering from acute mental disease. Having unstable extensive trauma. Taking immunosuppressant drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scar. Timepoint: 3 and 6 months after the intervention. Method of measurement: Vancouver Scar Scale, Patient and Observer Scar Assessment Scale and pathology. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of grafting. Timepoint: Days 5 and 7 during the first week of treatment. Method of measurement: Clinical examination.;Wound healing. Timepoint: Days 7, 14 and 21 after treatment. Method of measurement: Clinical examination, photography and pathology. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahnoush Momeni
Iran University of Medical Sciences
Outcome results
None listed