Skip to content

Effect of Quetiapine in Preventing Delirium in ICU Patients

Evaluation of the effect of quetiapine on the prevention of delirium in patients admitted to the intensive care unit (randomized clinical trial study)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180520039739N5
Enrollment
98
Registered
2023-06-20
Start date
2023-05-24
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patient admitted to the intensive care unit. Delirium due to known physiological condition

Interventions

Intervention 1: Intervention group: The intervention in this study involves administering quetiapine, a medication commonly used to treat psychiatric disorders. The dose of quetiapine given is 25 mg,

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Hospitalization in the intensive care unit Age over 18 years Patient satisfaction No alcohol addiction Healthy vision and hearing or elimination of vision and hearing defects by using glasses and hearing aids No use of psychoactive drugs

Exclusion criteria

Exclusion criteria: head trauma QT prolongation Encephalopathy Basal systolic blood pressure above 140 Basal diastolic blood pressure above 90 Tachycardia (beats more than 100 per minute) History of seizures Hypersensitivity to quetiapine intubated patient

Design outcomes

Primary

MeasureTime frame
Delirium Frequency. Timepoint: every 8 hours. Method of measurement: The number of episodes of delirium observed in an 8-hour period. This variable measures how often delusions occur in each group And it is measured using the Neecham criterion.;Severity of delirium. Timepoint: every 8 hours. Method of measurement: The intensity or severity of delirium symptoms experienced by participants was measured using the Neecham scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Habibzadeh siahroodkolaee

Esfahan University of Medical Sciences

gsmhabibzadeh@yahoo.com+98 31 3532 0551

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026