Treatment of pleural effusion by albumin and lasix

Evaluation of the use of albumin add-on therapy to loop diuretic for the management of pleural effusion in mechanically ventilated ill children

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180520039739N4

Enrollment

Registered

2020-02-17

Start date

2020-01-30

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pleural effusion. Pleural effusion, not elsewhere classified

Interventions

Intervention 1: Control group: treatment with furosemide (2 mg/kg

Aburaihan Company

Iran) plus 5 ml/kg of saline 0.9% as placebo for 3 days. Intervention 2: Intervention group: 1 gr/kg albumin 20% (5 ml/kg

Alborzdarou

Iran) plus furosemide (2 mg/kg

Iran) for three days.

Eligibility

Sex/Gender

All

Age

1 Years to 12 Years

Inclusion criteria

Inclusion criteria: ICU-admitted children Under mechanical ventilation Diagnosis of pleural effusion Age range of 1-12 years old Systolic blood pressure above 100 mmHg Serum albumin levels of less than 2.5 mg/dl

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Volume of pleural effusion. Timepoint: Every day up to 3 days. Method of measurement: FAST sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Habibzadeh

Esfahan University of Medical Sciences

gsmhabibzadeh@yahoo.com+98 913 389 1027

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026