Evaluation of effect of chlorhexidine on prevention of ventilator associated pneumonia

Comparison of the effect of Chlorhexidine mouthwash with Dine mouthwash on prevention of ventilator-associated pneumonia in pediatric intensive care unit

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180520039739N2

Enrollment

Registered

2018-11-26

Start date

2018-11-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator associated pneumonia.

Interventions

Intervention 1: Intervention group: treatment with 10 cc of 0.2% chlorhexidine gluconate mouthwash (Emad darou company) 3 times per day for 5 days. Intervention 2: Intervention group: treatment with 2

Eligibility

Sex/Gender

All

Age

2 Months to 14 Years

Inclusion criteria

Inclusion criteria: Patients with age of 2 months to 14 years Patients who need mechanical ventilation for at least 48 hours Admission in pediatric intensive care unit

Exclusion criteria

Exclusion criteria: Intubation before admission in PICU Oral or perioral lesions Immune deficiency Admission with causes of infectious or respiratory diseases Use of antibiotics before admission Sensitivity to herbal medication in past medical history

Design outcomes

Primary

Measure	Time frame
Incidence of pneumonia. Timepoint: In 5 days. Method of measurement: Infectious Diseases Society of America Guidelines and American Thoracic Society guidelines.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contact?Mohammadreza Habibzadeh

Esfahan University of Medical Sciences

gsmhabibzadeh@yahoo.com+98 913 389 1027

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026