Evaluation and comparison of the effectiveness of standard treatment with stand treatment plus Vitamin A in treatment in covid19 patients

Comparison of the effectiveness of standard treatment with stand treatment plus Vitamin A in treatment in covid19 patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180520039738N2

Enrollment

140

Registered

2020-04-10

Start date

2020-04-07

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corona virus disease 2019 (COVID-19). COVID-19, virus identified

Interventions

Intervention 1: Intervention group:25000 IU vitamin A per day for ten days, the plus, the standard national treatment for COVID 19. Intervention 2: Control group: the standard national treatment for C

Eligibility

Sex/Gender

All

Age

1 Years to 75 Years

Inclusion criteria

Inclusion criteria: Covid 19 patients Age over one year Age less than 75 years Tendency to participate in research Completion of informed written consent

Exclusion criteria

Exclusion criteria: pregnant women lactating women hepatitis B, C Autoimmune diseases Chronic renal failure (CRF) Liver failure Congestive heart failure (CHF) Chronic obstructive pulmonary disease (COPD)

Design outcomes

Primary

Measure	Time frame
Body temperature. Timepoint: before the start of the intervention and 10 days after the supplement Vitamin A. Method of measurement: Measureing body temperature with a thermometer through the mouth.;Blood oxygen saturation percentage. Timepoint: Before and ten days after starting treatment. Method of measurement: Pulse oximeter.;Cough rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Physical examination.;C-Reactive Protein (CRP) Test rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Complete blood count (CBC) Rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Creat. Rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Lymphocytes Rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Erythrocyte Sedimentation Rate (ESR) rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Number of breaths. Timepoint: Before and ten days after starting treatment. Method of measurement: Physical examination.;The pH of the blood. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Creatine phosphokinase (CPK) rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Lactate Dehydrogenase (LDH) rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Liver function tests rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.	—

Measure

Time frame

Body temperature. Timepoint: before the start of the intervention and 10 days after the supplement Vitamin A. Method of measurement: Measureing body temperature with a thermometer through the mouth.;Blood oxygen saturation percentage. Timepoint: Before and ten days after starting treatment. Method of measurement: Pulse oximeter.;Cough rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Physical examination.;C-Reactive Protein (CRP) Test rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Complete blood count (CBC) Rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Creat. Rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Lymphocytes Rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Erythrocyte Sedimentation Rate (ESR) rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Number of breaths. Timepoint: Before and ten days after starting treatment. Method of measurement: Physical examination.;The pH of the blood. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Creatine phosphokinase (CPK) rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Lactate Dehydrogenase (LDH) rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.;Liver function tests rate. Timepoint: Before and ten days after starting treatment. Method of measurement: Laboratory.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Rouhani

Saveh University of Medical Sciences

mohamadreza.rohani@yahoo.com+98 86 3368 4615

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026