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The effectiveness of bromelain on the amount of edema and ecchymosis after rhinoplasty

Investigating the effectiveness of bromelain on the amount of edema and ecchymosis after rhinoplasty versus placebo

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180519039720N2
Enrollment
46
Registered
2024-07-13
Start date
2023-08-23
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nose deformity. Acquired deformity of nose

Interventions

Intervention 1: In this Double -blind clinical trial, participants from 18 to 39 years of age who were scheduled for open preservation rhinoplasty and lateral osteotomy as one of the planning procedur
we only prescribed acetaminophen 500 mg every 6 hours to both groups. After obtaining informed consent, the inclusion and exclusion criteria were reviewed
then, all participants underwent open preservation rhinoplasty and lateral osteotomy during the surgery. After the procedure, a group of 23 people was randomly assigned to Bromelain 200 mg capsules (e

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: People who must have a lateral osteotomy in their surgery Not using dexamethasone during and after surgery Not using a cold compress after surgery. Absence of vascular disease Absence of coagulation disorders History of allergy to Bromelain or any of the pineapple products

Exclusion criteria

Exclusion criteria: Withdrawal from the study

Design outcomes

Primary

MeasureTime frame
Edema and Ecchymosis scoring after Rhinoplasty. Timepoint: At 1, 3, 7, 11 days after surgery. Method of measurement: Visual scoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBenyamin Rahmaty

Arak University of Medical Sciences

Benyamin.Rahmaty@gmail.com+98 912 334 0587

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026