Sudden Sensorineural Hearing Loss. Sudden idiopathic hearing loss, unspecified ear
Conditions
Interventions
Intervention 1: Control group: Prednisolone 1 mg/kg orally once a day for 10 days to improve pure tone audiogram(PTA). If there is improvement, prednisolone continues for another 10-day program and i
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Volunteers between 18 to 70 years old Sudden hearing loss over the last month
Exclusion criteria
Exclusion criteria: Other causes of hearing impairment, such as congenital deafness Brain tumors including cerebellopontine angle (CPA) neoplasms The concomitant use of warfarin and other anticoagulants A known metabolic disease such as Refsum disease Inherited bleeding disorders, such as hemophilia and Von Willebrand's disease and other bleeding disorders Abnormal international normalized ratio (INR), partial thromboplastin time (PTT), prothrombin time (PT) test results Corticosteroids Contraindications Lipid-lowering medications users, such as intestinal agents, statins,niacin and fibrates Lactation and Pregnancy Allergy to fish and fish oil
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pure Tone Audiogram “PTA”. Timepoint: Before intervention and 10,30 days after intervention. Method of measurement: Clinical audiometer (AC33). | — |
Secondary
| Measure | Time frame |
|---|---|
| Speech Recognition Threshold “SRT”. Timepoint: Before intervention,10 days, and 30 days after intervention. Method of measurement: Speech Audiometry by clinical audiometer (AC 33).;Word Recognition Score “WRS”. Timepoint: Before intervention,10 days, and 30 days after intervention. Method of measurement: Speech Audiometry by clinical audiometer (AC 33).;Tympanogram. Timepoint: Before intervention,10 days, and 30 days after intervention. Method of measurement: Tympanometry by tympanometer.;Acoustic Reflex Threshold “ART”. Timepoint: Before intervention,10 days, and 30 days after intervention. Method of measurement: Tympanometry by tympanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBenyamin Rahmaty
Tehran University of Medical Sciences
Outcome results
None listed