Comparison of efficacy of Traditional Medicine ( Zataria multiflora Boiss. and Trachyspermum Copticum (L.) Link) on Clinical symptom in patient with Irritable bowel syndrome (IBS)

Comparison of efficacy of two traditional medicine, Zataria multiflora Boiss and trachyspermum Copticum (L.) Link, on Clinical symptom in patient with Irritable bowel syndrome (IBS)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180519039707N1

Enrollment

150

Registered

2018-12-01

Start date

2018-09-06

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable bowel syndrome. Irritable bowel syndrome

Interventions

Intervention 1: Intervention group 1: consuming 750 mg capsule (Zataria multiflora Boiss and Trachyspermum Copticum (L.) Link), BID( in the morning and in the evening before meals) for 4 weeks. The re

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: fulfilling Rome III criteria for IBS Completion of the consent form Being at the age of 18 to 60 years old

Exclusion criteria

Exclusion criteria: Pregnancy Breast feeding History of gastrointestinal surgery Any serious drug-related inverse effect Inevitable weight loss History of any diseases like Crohn's disease and ulcerative colitis Dyspepsia Severe mental retardation Any kind of substance abuse or alcohol consumption Not completing the consent form The occurrence of warning signs (weight loss, anemia, Hematochezia or melena, dysphagia)

Design outcomes

Primary

Measure	Time frame
Quality of Life (QOL). Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: The quality of life questionnaire (IBS-QOL-34).;Pain. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.;Flatulence. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.;Constipation. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.;Diarrhea. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.;Difficulty in bowel movements. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.	—

Measure

Time frame

Quality of Life (QOL). Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: The quality of life questionnaire (IBS-QOL-34).;Pain. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.;Flatulence. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.;Constipation. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.;Diarrhea. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.;Difficulty in bowel movements. Timepoint: before the intervention, after 4 weeks, after 6 weeks (2 weeks after the interrupting the intervention). Method of measurement: Visual Analogue Scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Jamalizadeh Tajabadi

Kerman University of Medical Sciences

hjamalizadeh_14@yahoo.com+98 34 3226 8622

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026