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Low level laser and ozone in improvement of arthritis

Comparison of the low level laser versus intraarticular ozone on improving the osteoarthritis symptoms of knee joint

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180518039700N1
Enrollment
60
Registered
2018-07-19
Start date
2018-06-19
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis. Primary generalized (osteo)arthritis

Interventions

Intervention 1: Intervention group1(ozone therapy): In this group, patients undergoing ozone therapy for 3 times a week, for 6 sessions. Ozone is a colorless gas and an unstable form of oxygen that ha

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to No maximum

Inclusion criteria

Inclusion criteria: Median knee osteoarthritis (Grade 2 or 3 based on Kellegren and Lawrence knee radiography) Patients over 45 years old Satisfaction of patients participating in the study Failure to respond to conservative and physiotherapy treatments over the past 6 months

Exclusion criteria

Exclusion criteria: Contraindication of laser therapy (pregnancy, epilepsy, cardiac pacemaker, hyperthyroidism, cancer) Contraindication of ozone therapy (epilepsy, coagulopathy, recent heart attack, hyperthyroidism, thrombocytopenia, G6PD deficiency) Corticosteroid consumption in the last three months previous Knee surgery Ankylosis Varus or Valgus deformity of knee

Design outcomes

Primary

MeasureTime frame
Physical performance. Timepoint: At the beginning of the study, 6th session of laser therapy and 3rd session of ozone therapy and the end of the sessions of both methods. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index questionnaire (WOMAC questionnaire).;Pain score. Timepoint: At the beginning of the study, 6th session of laser therapy and 3rd session of ozone therapy and at 12th session of laser therapy and 6rd session of ozone therapy. Method of measurement: visual analogue scale.;Range of motion of knee joint. Timepoint: At the beginning of the study, 6th session of laser therapy and 3rd session of ozone therapy and the end of the sessions of both methods. Method of measurement: Goniometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSolmaz Fakhari

Tabriz University of Medical Sciences

solmaz_fakhari@yahoo.com+98 41 3329 6124

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026