Poor Ovarian Responder. Other primary ovarian failure
Conditions
Interventions
Intervention 1: Intervention group: Daily oral administration of 4gr of ]nofolic powder (myoinositol + folic acid) for 12 weeks in patients with poor ovarian responder. Intervention 2: Control group:
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 43 Years
Inclusion criteria
Inclusion criteria: All women of reproductive age with reduced ovarian reserve (number of Antral follicles less than 7) All women of reproductive age with decreased in anti-mullerian hormone to less than 1.2 ng/ml All women of reproductive age over than 40 years Having one of the above criteria is a prerequisite for entry into the study
Exclusion criteria
Exclusion criteria: Presence of endocrine and metabolic disorders such as polycystic ovary syndrome, hyperprolactinemia, diabetes and thyroid dysfunction Pelvic pathology such as hydrosalpinx, uterine anomaly Stages III to IV endometriosis and fibroma Male factors infertility such as Oligo-Astheno-Teratozoospermia (OAT) or Azoospermia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oocyte Quility. Timepoint: 2-3 hr after oocyte collection. Method of measurement: Microscopic Evaluation.;Fertilization Rate. Timepoint: 24 hr after Injection. Method of measurement: Microscopic Evaluation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical Pregnancy Rate. Timepoint: 2 weeks after embryo transfer. Method of measurement: B-HCG evaluation.;Clinical pregnancy rate. Timepoint: 7 weeks after embryo transfer. Method of measurement: Sonography for fetal heart rate. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Azizi Kutenaei
Bandare-abbas University of Medical Sciences
Outcome results
None listed