Effects of taurine in diabetic foot ulcer

Study of the effects of taurine supplementation on wound healing and metabolic status in patients with diabetic foot ulcer

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180514039657N2

Enrollment

Registered

2019-05-26

Start date

2019-05-22

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Foot Ulcer. Diabetic ulcer

Interventions

Intervention 1: Intervention group: 25 patients with diabetic foot ulcers take one 500 mg thorium capsule three times per day (1500 mg daily) for 30 days. To control the correct use of pills, cans are

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Diabetic foot ulcer grade 3 based on Wagner-Meggitt's benchmark More than 5 years of illness Patients with type 2 diabetes

Exclusion criteria

Exclusion criteria: The use of alternative therapies, including hormones or vitamin supplements Pregnant or lactating women Chronic kidney disease Chronic liver disease Chronic Pulmonary Disease Chronic or acute inflammatory diseases Heart valve disease Short Bowel Syndrome Allergy Patients with low immune system (autoimmune)

Design outcomes

Primary

Measure	Time frame
Fasting insulin. Timepoint: The beginning and end of the study. Method of measurement: ELISA.;Serum triglyceride. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;Total cholesterol. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;LDL-C. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;HDL-C. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;Fasting Blood Glucose. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;Hs-CRP. Timepoint: The beginning and end of the study. Method of measurement: ELISA.;Fructosamine. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;Nitric Oxide. Timepoint: The beginning and end of the study. Method of measurement: Spectrophotometry.;Oxidized glutathione. Timepoint: The beginning and end of the study. Method of measurement: Spectrophotometry.;Wound healing. Timepoint: The beginning and end of the study. Method of measurement: Wagner-Meggitt’s classification.	—

Measure

Time frame

Fasting insulin. Timepoint: The beginning and end of the study. Method of measurement: ELISA.;Serum triglyceride. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;Total cholesterol. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;LDL-C. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;HDL-C. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;Fasting Blood Glucose. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;Hs-CRP. Timepoint: The beginning and end of the study. Method of measurement: ELISA.;Fructosamine. Timepoint: The beginning and end of the study. Method of measurement: enzymatic method.;Nitric Oxide. Timepoint: The beginning and end of the study. Method of measurement: Spectrophotometry.;Oxidized glutathione. Timepoint: The beginning and end of the study. Method of measurement: Spectrophotometry.;Wound healing. Timepoint: The beginning and end of the study. Method of measurement: Wagner-Meggitt’s classification.

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Secondary

Measure	Time frame
Weight. Timepoint: The beginning and end of the study. Method of measurement: scale.;Body Mass Index. Timepoint: The beginning and end of the study. Method of measurement: weight (kg) divided to height square.;Systolic Blood Pressure. Timepoint: The beginning and end of the study. Method of measurement: Measuring blood pressure.;Diastolic Blood Pressure. Timepoint: The beginning and end of the study. Method of measurement: Measuring blood pressure.	—

Measure

Time frame

Weight. Timepoint: The beginning and end of the study. Method of measurement: scale.;Body Mass Index. Timepoint: The beginning and end of the study. Method of measurement: weight (kg) divided to height square.;Systolic Blood Pressure. Timepoint: The beginning and end of the study. Method of measurement: Measuring blood pressure.;Diastolic Blood Pressure. Timepoint: The beginning and end of the study. Method of measurement: Measuring blood pressure.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasih Namjoonia

Ahvaz University of Medical Sciences

masih.namjoo@gmail.com+98 61 3333 3050

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026