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The effect of Vitamin D on the prevention of statin associated muscle complications

The effect of vitamin D replacement therapy on the incidence of statin associated muscle complications

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180513039645N1
Enrollment
80
Registered
2018-07-16
Start date
2016-12-20
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic heart disease. Acute ischemic heart disease, unspecified

Interventions

Intervention 1: Intervention group: : Vitamin D 3, 300,000 units
one dose
muscular. Intervention 2: Control group: Sterile water ampule
1mililiter
muscular.

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 84 Years

Inclusion criteria

Inclusion criteria: All patients who have been recently treated with atorvastatin

Exclusion criteria

Exclusion criteria: Previous history of statin use Previous history of Vitamin D Supplement use having musculoscletal symptoms history of musculoscletal disease history of thyroid disease

Design outcomes

Primary

MeasureTime frame
Statin associated muscle symptom score. Timepoint: At the beginning of the study, 1, 2 and 3 months after the start of taking statin and administering vitamin D and placebo. Method of measurement: Statin associated Muscle Symptom Score Questionnaire.;Serum Creatine Kinase level. Timepoint: At the beginning of the study and 3 months later. Method of measurement: By the laboratory.

Secondary

MeasureTime frame
Cholesterol. Timepoint: At the beginning of the study and 3 months later. Method of measurement: By the laboratory.;Fasting blood sugar. Timepoint: At the beginning of the study and 3 months later. Method of measurement: By the laboratory.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahid Kabiri Rad

Mashhad University of Medical Sciences

Kabiriradv2@mums.ac.ir+98 51 3611 1357

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026