Studying of Black Seed effect on colorectal cancer

Studying of Black Seed effect as a complementary chemotherapy treatment on biomarkers of patients with colorectal cancer

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180513039641N1

Enrollment

100

Registered

2018-08-29

Start date

2018-07-23

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Colorectal cancer. Condition 2: colon cancer. Condition 3: rectum cancer. Malignant neoplasm of rectosigmoid junction Malignant neoplasm of colon Malignant neoplasm of rectum

Interventions

Black seed capsule (containing fresh black seed powder) in the amount of 1000 mg three times a day (it is better to take black seed capsule 2 hours before or 2 hours after a meal)..

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age between 20 and 70 years Patients who are aware of their colorectal cancer disease Performing colorectal cancer Surgery The existence of colorectal cancer-Stage IIb and III The first time achieving chemical therapy after colorectal cancer surgery

Exclusion criteria

Exclusion criteria: Pregnant and lactating women and married women in childbearing age who do not use reliable contraceptive methods

Design outcomes

Primary

Measure	Time frame
Cancer antigen 19-9 (CA19-9). Timepoint: Baseline, 3 months following the treatment and the end of treatment. Method of measurement: Blood test.;Carcino Embryonic Antigen (CEA). Timepoint: Baseline, 3 months following the treatment and the end of treatment. Method of measurement: Blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHoda Abolhasani

Ghoum University of Medical Sciences

hodaabolhasani@gmail.com+98 25 3320 9071

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026