Evaluation of analgesic effects of diclofenac sodium and ketorolac in root canal therapy

Comparasion of the Effect of Diclofenac Sodium and Ketorolak on Post Endodontic Pain in Mandibular first Molars with Symptomatic Irreversible Pulpitis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180513039638N1

Enrollment

Registered

2021-04-04

Start date

2021-04-08

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain in tooth. Acute apical periodontitis of pulpal origin

Interventions

Intervention 1: Intervention group: In this group, diclofenac sodium 100 mg analgesic made by Shafa is taken as an oral tablet and a single dose before starting treatment. Intervention 2: In this gro

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: patient who requires root canal treatment of the first mandibular molars with irreversible pulpitis Between the ages of 18 and 60

Exclusion criteria

Exclusion criteria: Being in late pregnancy or breastfeeding Having Asthma or any allergies to diclofenac sodium or ketorolac History of gastrointestinal diseases such as stomach ulcers History of Bleeding disorders Intention to perform heart bypass surgery after receiving medication

Design outcomes

Primary

Measure	Time frame
Intensity of pain. Timepoint: Measurement of patient's toothache immediately before treatment and at 6, 12 and 24 hours after treatment. Method of measurement: Visual Analog Scale Pain Assessment Form.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contact???? ?????? ???????

Oroumia University of Medical Sciences

Abdollahi.am@umsu.ac.ir+98 44 3223 4897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026