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Effect of Curcumin supplementation on muscle damage

Effects of curcumin supplementation in comparison with placebo on serum creatinine kinase (CK), lactate dehydrogenase (LDH), malonyl dialdehyde (MDA), total antioxidant capacity (TAC), and interleukin-6 (IL-6) after taekwondo race in taekwondo men

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180513039637N3
Enrollment
19
Registered
2020-05-24
Start date
2018-05-01
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dose not apply.

Interventions

Intervention 1: Intervention group: 9 male Taekwondoers who took curcumin supplements (4 g/d) for 5 days. 3 days after eating curcumin, subjects participated in Taekwondo competition (3 races with 30

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
19 Years to 27 Years

Inclusion criteria

Inclusion criteria: At least 3 years of experience in taekwondo competitions Athletes' maximum oxygen consumption (VO2 max) should be more than 45 percent

Exclusion criteria

Exclusion criteria: Having a history of diabetes Having a history of cardiovascular disease Having a history of respiratory disease Having food allergies Having a drug allergy Use of inflammatory agents before or during the study Use a sports supplement before or during the study Use the drug before or during the study

Design outcomes

Primary

MeasureTime frame
Serum creatine kinase (CK) level in taekwondo athletes. Timepoint: Blood sampling was performed before the start of supplementation (3 day before the race), one hour before the race, immediately after the race, 24 hours and 48 hours after the race (5 stages). Method of measurement: Creatine kinase kit.;Serum lactate dehydrogenase (LDH) level in taekwondo athletes. Timepoint: Blood sampling was performed before the start of supplementation (3 day before the race), one hour before the race, immediately after the race, 24 hours and 48 hours after the race (5 stages). Method of measurement: lactate dehydrogenase kit.;Serum Malonyl Dialdehyde (MDA) Levels in Taekwondo Athletes. Timepoint: Blood sampling was performed before the start of supplementation (3 day before the race), one hour before the race, immediately after the race, 24 hours and 48 hours after the race (5 stages). Method of measurement: Malonyl Dialdehyde kit.;Serum total antioxidant capacity (TAC) levels in Taekwondo athletes. Timepoint: Blood sampling was performed before the start of supplementation (3 day before the race), one hour before the race, immediately after the race, 24 hours and 48 hours after the race (5 stages). Method of measurement: total antioxidant capacity kit.;Serum Interleukin-6 (IL-6) Level in Taekwondo Athletes. Timepoint: Blood sampling was performed before the start of supplementation (3 day before the race), one hour before the race, immediately after the race, 24 hours and 48 hours after the race (5 stages). Method of measurement: Interleukin-6 kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHadi Pourmanaf

Tabriz University of Medical Sciences

hadi.pvrmnaf@ut.ac.ir+98 41 3667 3861

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026