Comparison between Bromelain and Ibuprofen for postoperative pain control following dental implant placement surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180513039628N1

Enrollment

Registered

2018-08-29

Start date

2018-07-16

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain control following dental implant placement surgery. Diseases of oral cavity, salivary glands and jaws

Interventions

Intervention 1: Intervention group : in intervention group Bromelin ,500 mg (Bromelain500-Parmoon Amin -Iran-Tehran) was prescribed an oral tablet for 5 days every 8 hours.Post-operative pain is initi

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Applicants without illness over the age of 18 who have not consumed any medication in the last two weeks. Applicant to replacement of missing teeth with implants in the first and second premolar regions of the maxilla or mandible. Based on CBCT assessments, there is a sufficient amount of bone in the toothless areas without the need for recovery and reconstruction.

Exclusion criteria

Exclusion criteria: Applicants with systemic diseases that are treated with other medications Smokers and alcoholics Applicants with poor oral hygiene Applicants who need bone graft Applicants who need more than two implants Applicants with surgical duration more than 45 minutes

Design outcomes

Primary

Measure	Time frame
Pain intensity. Timepoint: day 1, 3 and 6 after surgery. Method of measurement: Visual analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhang Mahboub

Tabriz University of Medical Sciences

mahboubif@tbzmed.ac.ir+98 41 3335 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026