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Effect of cinopar in mandibular fracture

Evaluation of the effect of teriparatide (cinopar)on bone healing in mandibular fracture

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180507039576N1
Enrollment
30
Registered
2021-06-18
Start date
2021-05-22
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mandibular bone fracture. Fracture of mandible, unspecified

Interventions

Intervention 1: Intervention group:In this group, in addition to routine drug therapy, cinopar ampoule (8 micrograms per kilogram daily for one month) which is produced by Cinnagen company is injected

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 18-60 year Mandibular fracture Open reduction and internal fixation

Exclusion criteria

Exclusion criteria: Infection Patient with a history of fracture Patient taking immunosuppressive, corticosteroid and digoxin The level of calcium greater than 10

Design outcomes

Primary

MeasureTime frame
Bone healing. Timepoint: Before surgery and one month after surgery. Method of measurement: Evaluated both qualitatively, based on subjective fracture line changes , and quantitatively based on Hounsfield unit .

Secondary

MeasureTime frame
Pain. Timepoint: 7, 14, 21, 28 days after surgery. Method of measurement: Visual Analogue Scale.;Swelling. Timepoint: 7, 14, 21, 28 days after surgery. Method of measurement: Examination.;Ecchymosis. Timepoint: 7, 14, 21, 28 days after surgery. Method of measurement: Examination.;Pus discharge. Timepoint: 7, 14, 21, 28 days after surgery. Method of measurement: Examination.;Dehiscence. Timepoint: 7, 14, 21, 28 days after surgery. Method of measurement: Examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayyeh Ebrahimi

Yazd University of Medical Sciences

Ebrahimi_6920@yahoo.com+98 51 8223 2306

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026