The effects of beta-hydroxy beta-methyl butyrate HMB supplementation with selected resistance training on Liver, Muscular, Kidney Enzymes, Lipid Profile, Body Combination, Strength and Some Other Physical Fitness Factors in Bodybuilding Athletes

The effects of beta-hydroxy beta-methyl butyrate HMB supplementation with selected resistance training on some biochemical factors of blood and strength in bodybuilding athletes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180503039517N4

Enrollment

Registered

2020-07-14

Start date

2019-05-05

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

supplementation in body builders.

Interventions

Intervention 1: The experimental group performed selected resistance exercises for 8 weeks and 3 sessions per week and received HMB supplement in the amount of 3 g per day as two suckers for 14 days.

Eligibility

Sex/Gender

Male

Age

19 Years to 29 Years

Inclusion criteria

Inclusion criteria: Age (19-29years) Gender (male) a maximum of 3 months involving in resistance exercise

Exclusion criteria

Exclusion criteria: smoking having cardiorespiratory, musculoskeletal, neurological, hormonal or orthopedic disorders No ingestion of androgenic and energetic supplements in the past 1 months

Design outcomes

Primary

Measure	Time frame
Serum levels of liver enzymes (Aspartate transaminase (AST) and Alanine transaminase (ALT). Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using the Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method.;Serum levels of muscle enzymes (Creatine kinase (CK) and lactate dehydrogenase (LDH)). Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method.;Serum levels of renal function enzymes (the blood urea nitrogen (BUN), Creatinine and Urea. Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using the Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method.;Serum levels of Lipid profile (low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, Total cholesterol and triglycerides. Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using Biosystems Laboratory kit (made in Spain), according to the manufacturer's instructions and the ELISA method.;Some physical fitness factors (strength, body composition and power). Timepoint: Init	—

Measure

Time frame

Serum levels of liver enzymes (Aspartate transaminase (AST) and Alanine transaminase (ALT). Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using the Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method.;Serum levels of muscle enzymes (Creatine kinase (CK) and lactate dehydrogenase (LDH)). Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method.;Serum levels of renal function enzymes (the blood urea nitrogen (BUN), Creatinine and Urea. Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using the Pars Azmoun laboratory kit (made in Iran) according to the manufacturer's instructions and the ELISA method.;Serum levels of Lipid profile (low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, Total cholesterol and triglycerides. Timepoint: Initial blood sampling will be performed in the pre-test phase two days before the start of the study, and final blood sampling will be performed in the post-test phase two days after the end of the study in the laboratory. Method of measurement: Using Biosystems Laboratory kit (made in Spain), according to the manufacturer's instructions and the ELISA method.;Some physical fitness factors (strength, body composition and power). Timepoint: Init

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoleyman Ansari Kolachahi

Islamic Azad University

solomonansari@yahoo.com+98 911 230 6198

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026