Autism Spectrum Disorder. Autistic disorder
Conditions
Interventions
Intervention 1: Intervention group: Children in the aquatic exercise group will be examined by a physician to obtain permission to participate in the training sessions and will participate in water ex
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
Male
Age
8 Years to 14 Years
Inclusion criteria
Inclusion criteria: Gender: Boy (8-14 years old) Having autism grade 1 and 2 (the diagnosis of autism severity will be made by a specialist psychologist according to the Gars-2 scale) Taking risperidone for at least one year to reduce behavioral or sleep problems in children
Exclusion criteria
Exclusion criteria: having cardiovascular, musculoskeletal, and metabolic diseases limiting physical activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Insulin resistance indicators. Timepoint: 48 hours before the intervention and 48 hours after 10 weeks of intervention. Method of measurement: Blood samples were taken in two stages, 48 ??hours before and after 8 weeks of intervention, after a 12-hour overnight fast, in the amount of 10 cc of blood, in a sitting position, from the brachial vein.;Metabolic syndrome indicators. Timepoint: 48 hours before the intervention and 48 hours after 10 weeks of intervention. Method of measurement: Metabolic syndrome indicators including systolic and diastolic blood pressure, triglycerides, HDL, and waist-to-hip circumference are measured. | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver enzymes. Timepoint: 48 hours before the intervention and 48 hours after 10 weeks of intervention. Method of measurement: Serum AST and ALT levels will be measured before and after the intervention with a photometric method by the Dialab Laboratory kit (Austrian -made).;Kidney function indicators. Timepoint: 48 hours before the intervention and 48 hours after 10 weeks of intervention. Method of measurement: Serum levels of urea, creatinine, and BAN indicators are measured before and after the intervention using Biotechnical Autoanalyzer (made in Italy).;Hematological indicators. Timepoint: 48 hours before the intervention and 48 hours after 10 weeks of intervention. Method of measurement: White and red blood cells, hematocrit, and platelets will be measured using the Cell Counter (made of Japan).;Thyroid hormones. Timepoint: 48 hours before the intervention and 48 hours after 10 weeks of intervention. Method of measurement: Thyroid hormones including T3 and T4 will be measured using Immunoassay AIA 360 (Made in America).;Adipokines. Timepoint: 48 hours before the intervention and 48 hours after 10 weeks of intervention. Method of measurement: Adipokines including adiponectin, Leptin, Resistin, and Asprosin will be measured through Elisa using the Shanghai Sunteam Biotech (made of China).;Lipid profile. Timepoint: 48 hours before the intervention and 48 hours after 10 weeks of intervention. Method of measurement: Normal values of serum triglyceride, total cholesterol, LDL, and HDL levels will be measured through Photometry Method Using Pars azmoon kit (Made in Iran). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFahimeh AdibSaber
Islamic Azad University
Outcome results
None listed