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efficacy of erythrocyte transfusion in mortality rate of patients with aluminum phosphide

Comparison of efficacy of erythrocyte transfusion in mortality rate of patients with aluminum phosphide contamination with coservative treatmnt: A study of randomized clinical trials

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180428039443N1
Enrollment
140
Registered
2019-01-07
Start date
2018-10-23
Completion date
Unknown
Last updated
2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aluminium phosphide poisoning. Toxic effect of pesticides

Interventions

Intervention 1: Intervention group: Patients who receive, in addition to standard treatment, fresh packed RBC transfusion (transmitted by the blood transfusion center). Intervention 2: Control group:

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years More than 1/4 tablets of rice (aluminum phosphide) They have not been poisoned for more than 4 hours. Clinical manifestations (garlic smell, hypotension (less than 60/100 mm / Hg), gastrointestinal tract pain (retinoestromem, vomiting) Laboratory disorder including metabolic acidosis (less than 7.2)

Exclusion criteria

Exclusion criteria: People who have taken herbal pill (Banana). History of any known chronic disease (high hemoglobin, congestive failure) due to clinical diagnosis. pregnant women lactating woman History of response to blood transfusion Patients with CHF (do not have transfusion bearing erythrocyte) Patients with hemoglobin above 16

Design outcomes

Primary

MeasureTime frame
Metabolic acidosis,. Timepoint: The moment of arrival, one hour after arrival, two hours after arrival, three hours after arrival, six hours after arrival, twelve hours after arrival, twelve and four hours after arrival, forty eight hours after arrival, seventy And hours after arrival. Method of measurement: Metabolic acidosis is estimated by measuring the level of acidity in the blood.;Mortality rate. Timepoint: From the time of arrival to the moment of discharging from the hospital. Method of measurement: The mortality rate is also obtained by the number of treated patients compared to the referrals.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Reza Dehpour

Tehran University of Medical Sciences

dehpoura@sina.tums.ac.ir+98 21 8897 3652

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026