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Studying the effectiveness of Urtica on reducing fatigue associated with non-metastatic breast cancer

Evaluating the effectiveness of Urtica on reducing cancer-related fatigue in female patients with non-metastatic breast cancer: A randomized, double-blind, controlled clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180426039421N4
Enrollment
80
Registered
2025-02-24
Start date
2025-03-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-metastatic breast cancer.

Interventions

Intervention 1: Intervention group: Urtica syrup containing nettle extract (standardized product based on at least 0.04 mg/ml chlorogenic acid, Zardband Company, Tehran, Iran) will be taken twice dail

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Breast cancer according to pathology report Age over 18 years Informed consent Candidate for adjuvant chemotherapy and radiotherapy

Exclusion criteria

Exclusion criteria: Die during treatment Having depression or taking antidepressants during the follow-up period The occurrence of metastasis Breast cancer with estrogen or progesterone hormone receptor-positive cells that are candidates for hormone therapy Methylphenidate use Taking warfarin or other anticoagulant medications Systolic blood pressure less than 100 mmHg Long-term use of painkillers, alcohol, or illegal drugs Allergy to Urtica based on history taking Patients with any systemic disease Have received neoadjuvant treatment Pregnancy or breastfeeding Hemoglobin less than 12

Design outcomes

Primary

MeasureTime frame
Fatigue. Timepoint: 4 weeks after treatment. Method of measurement: Based on the brief fatigue questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Kesht pour amlashi

Hamedan University of Medical Sciences

z.keshtpour@edu.umsha.ac.ir+98 81 3838 1938

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026