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Comparison of letrozole alone with letrozole and N-Acetylcysteine for pregnancy rate in polycystic ovary syndrome patient who were undergoune induction

Comparison of letrozole alone with letrozole and N-Acetylcysteine for pregnancy rate in polycystic ovary syndrome patient who were undergoune induction

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180425039418N2
Enrollment
162
Registered
2018-12-15
Start date
2018-10-23
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Polycystic ovarian syndrome. Condition 2: pregnancy. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group 1: this randomized clinical trial will be done on patients with poly cystic ovarian disease who randomly will be selected as intervention and control group . the con

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: presence of two of oligo/involution criteria clinical or laboratory based evidences of hyperendrogenism and polycystic ovaries in sonography

Exclusion criteria

Exclusion criteria: thyroid and prolactin dysfunction tubal abnormalities leading to infertility medium to severe semen fluid abnormalities of sperm quantity, mobility and shape leading to infertility presence of cysts(larger than 6 cm), history of asthma and usage of drugs influencing on glucose metabolism within 3 month before study entrance

Design outcomes

Primary

MeasureTime frame
The number of pregnancies. Timepoint: since the third day through seventh day after menstruation, 5 mg Letrozole was given to the group of control for 5 days and 5 mg Letrozole and 1200mg N-acetylcycteine were given to the group of intervention. Method of measurement: the structured checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSedigheh Mollashahi

Zahedan University of Medical Sciences

salahi13639@gmail.com+98 54 3329 5744

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026