premenstrual syndrome.
Conditions
Interventions
Intervention 1: 80 students and medical staff of Iran University of Medical Sciences receive synbiotic supplement with 10 microbial population to 9 colonies per gram, containing (Lactobacillus gasser
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Age range 18-40 years BMI Between 35 and 25 Affection of premenstrual syndrome based on PSST questionnaire The normal duration of bleeding (3-7 days in the 3 months before entering the study) and the regular monthly cycle Lack of chronic systemic diseases and diseases related to the ovary Lack of liver disease, bile duct disease, gastrointestinal and intestinal diseases, kidney disease, parathyroid thyroid and non-hyperphosphatemia Non-use of probiotic and probiotic-based supplements over the past 6 months Not using supplements containing vitamins and minerals supplement W3 or fish oil Non-development of neurological diseases and no use of psychosomatic drugs Non-use of hormonal drugs The desire to participate in the study and written consent written consent Absence of iron deficiency anemia Non-use of steroidal and non-steroidal anti-inflammatory drugs, Anti epileptic drugs, anti cholesterolemic drugs, anti-acid drugs, diuretics and laxatives Not using any medication or dietary supplement that affects weight
Exclusion criteria
Exclusion criteria: Consumption of probiotic supplementation from 3 months before study Affection of acute and chronic diseases of depression Iron deficiency anemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: questionnaire Before intervention and 1.2 and 3 months after the intervention.;BMI. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: Weight ratio (kg) to squared height (m).;Waist circumference. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: meter.;Nutritional status. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: Measurement of energy and nutrients intake using 24-hour dietary recall method and anthropometric measurement using scale and stadiometer.;Physical Activity. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: IPAQ questionnaire.;Quality of life. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: ququestionnaire.;Fat percent. Timepoint: Before the intervention, 1.2 and 3 months after the intervention. Method of measurement: enbody. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mitra Zarrati
Iran University of Medical Sciences
Outcome results
None listed