evaluation of effect of bupivacaine and clonidine on pain control after laparoscopic cholecyctectomy

comparison of the effectiveness of intraperitoneal bupivacaine with clonidine on reduction of pain after laparoscopic cholecyctectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180424039401N1

Enrollment

Registered

2018-05-25

Start date

2017-12-21

Completion date

Unknown

Last updated

2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: acute cholecystitis. Condition 2: chronic cholecystitis. Condition 3: cholelithiasis. Calculus of gallbladder with acute cholecystitis Calculus of gallbladder with chronic cholecystitis without obstruction Cholelithiasis

Interventions

Intervention 1: Intervention group: intrapetoneal bupivacaine 0.5% 20cc. Intervention 2: Intervention group: 0.15 miligram tab clonidine 1.5 hour before surgery. Intervention 3: Control group: 20cc n

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: patients bethween 18-65years old with cholecyctitis patients bethween 18-65years old with symptomatic cholelithiasis

Exclusion criteria

Exclusion criteria: patients with Allergy history to the aneshtetic agent severe cardiac disease severe lung disease patients with conversion to open cholecystectomy

Design outcomes

Primary

Measure	Time frame
Abdominal pain. Timepoint: 1 hour after operation. 6 hour after operation. 24 hour after operation. Method of measurement: visual analogue score.;Pain killer consumption. Timepoint: during 24 hours after surgery. Method of measurement: computing pain killer consumption.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Nasrin Rahmani

Sari University of Medical Sciences

farzad_mokhtari_s@yahoo.com+98 11 3324 4496

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026