Statins myopathy. Drug-induced myopathy
Conditions
Interventions
Intervention 1: Control group: For all patients Pearl, 50,000 units of vitamin D (Zahravi Company) will be given orally once a week for 8 weeks. ". Intervention 2: Intervention group: For all patient
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. There are symptoms of myalgia with statins 2. Age of patients aged 18 to 65 years. 3. Lower levels of vitamin D (25OH Vitamin D3) from normal range (<32ng / ml).
Exclusion criteria
Exclusion criteria: 1. Patient does not provide consent. 2. Failure to complete the study 3. Age under 18 and over 65 years. 4. Alcohol or substance abuse. 5. Collagen disease, vascular, coagulopathy, genetic, cerebrovascular disease. 6. Creatine kinase level above 300U / L, indicating fibromyalgia. 7. The patient is not able to use Pearl vitamin D3 or a tendency to inject a drug. 8. The history and evidence of examination indicate trauma in the organs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| "Measuring serum level of vitamin D3". Timepoint: "Measuring serum level of vitamin D3 at the beginning of the study (before the intervention) and at the end of the study (8 weeks after starting vitamin D)". Method of measurement: Serum levels of vitamin D were measured using ELISA method.;"Measuring the severity of myopathy pain". Timepoint: "Measuring the severity of pain at the beginning of the study (before the intervention) and 8 weeks after taking vitamin D". Method of measurement: "Visual Analogue Scale (VAS)". | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza ganji
Ahvaz University of Medical Sciences
Outcome results
None listed