The effect of rehabilitation on respiratory symptoms and lung function indexes

The effect of rehabilitation (strength and endurance exercises) on respiratory symptoms, lung function indexes and some inflammatory mediators in asthmatic patients.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180418039348N2

Enrollment

Registered

2018-07-14

Start date

2018-07-11

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. J45

Interventions

Intervention group: Exercise exercises will be done for 4 weeks (3 sessions per week). During each session after warming up, for 10 minutes, endurance training includes treadmills, bicycle and arm erg

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Mild to moderate bronchial asthma disease based on spirometric testing and having clinical symptoms of respiratory tract Absence of acute illnesses that are in contradiction with exercise Age limit 20 to 60 years Giving written consent Having a commitment to doing research steps

Exclusion criteria

Exclusion criteria: Severe asthma that is exacerbated by exercise Acute diseases that are exacerbated by exercise Cardiovascular disease Chronic inflammatory diseases Acute infections Malignant diseases Having autoimmune diseases and immune deficiency

Design outcomes

Primary

Measure	Time frame
Improvement in respiratory status and spirometry tests. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Measurement with using a spirometer device and pulmonary function tests.;Measuring cytokines and inflammatory mediators ( such as IgE ? IgG TNFa, IL-6 and IL-8 ) in serum. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.;Total number and types of white blood cells in the blood. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Using a special laboratory device for counting white blood cells.	—

Measure

Time frame

Improvement in respiratory status and spirometry tests. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Measurement with using a spirometer device and pulmonary function tests.;Measuring cytokines and inflammatory mediators ( such as IgE ? IgG TNFa, IL-6 and IL-8 ) in serum. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.;Total number and types of white blood cells in the blood. Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Using a special laboratory device for counting white blood cells.

—

Secondary

Measure	Time frame
Measurement concentration of fractional exhaled nitric oxide (FeNO). Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.;Measurement of C-reactive protein (CRP). Timepoint: At the beginning of the study and 30 days after the start of the study. Method of measurement: Use of special kits and protocols.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Boskabadi

Mashhad University of Medical Sciences

boskabadij901@mums.ac.ir+98 51 3882 8883

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026