Noninflammatory disorder of female genital tract. Complication associated with artificial fertilization ,unspecified
Conditions
Interventions
Intervention 1: Control group: Continue estradiol since day 2 of cycle till end of study. Intervention 2: Intervention group: Infusion of 0.5 cc of platelet rich plasma( PRP)that contained platelet 4
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Healthy women between 18 and 40 years old BMI below 30 kg / m 2 Have at least 3 or more unsuccessful fetal transmissions Fetal removal candidate
Exclusion criteria
Exclusion criteria: Hemoglobin disorders (hemoglobin less than 11 mg / ml and platelet below 150,000) Immunological disorders Hormonal disorders of genetic and chromosomal anomalies Acute infection Uterus anomalies including the unicorn uterus (whether or not surgical) arcuate History of uterine enzymes such as myomectomy and cesarean section NSAID use within 10 days before intervention Corticosteroid use over the past 1 month Smoking Fever History of malignancy Coagulation disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fetal Vision Imaging. Timepoint: Week 5 after ET. Method of measurement: Vaginal ultrasound.;Fetal heartburn. Timepoint: Week 5 after ET. Method of measurement: Vaginal ultrasound.;Endometrial thickness. Timepoint: in 10th day of cycles and 72 hr after infusion of PRP. Method of measurement: Trans vaginal sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Determine the amount of implantation. Timepoint: 4week after embryo transfer. Method of measurement: Trans vaginal sonography.;Clinical pregnancy or miscarriage. Timepoint: 4week after embryo transfer. Method of measurement: Trans vaginal sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Fatemeh Aghajanzadeh
Babol University of Medical Sciences
Outcome results
None listed