Loss of teeth due to extraction. Loss of teeth due to extraction
Conditions
Interventions
Intervention 1: Intervention group: After the extraction of the tooth with a periapical lesion in the first intervention group, 20 milliliters of blood sample is taken from the patient, and using a ce
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Healthy patient in terms of systemic diseases Remaining roots Soft tissue and buccal bone plate in a normal distance from the CEJ Plaque index less than 25% Teeth with peri-apical lesion
Exclusion criteria
Exclusion criteria: Smoking Pregnancy History of radiotherapy and chemotherapy Active infection Type 2 and 3 socket Advanced periodontitis and marginal bone recession Blood disease and diabetes Periapical lesion larger than 7 millimeter Bruxism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: 1 hour post-surgery, 6 hours post-surgery, 24 hours post-surgery, 48 hours post-surgery. Method of measurement: Using Visual Analog Scale (VAS) which ranges from 0 to 10. So that, 0 indicates no pain and 10 indicates severe pain.;The healing of soft tissue. Timepoint: Immediately after the surgery, 1 month after the surgery, 3 months after the surgery, 6 months after the surgery. Method of measurement: Using Early Healing Index (EHI) which ranges from 0 to 4. 0 means complete closure of flap without fibrin line. 1 means complete closure of flap with thin fibrin line. 2 means complete closure of flap with fibrin clot. 4 means no closure of flap with partial necrosis. and 5 means no closure of flap with complete necrosis.;The healing of the peri-apical lesion. Timepoint: Immediately after the surgery, 3 months after the surgery, 6 months after the surgery. Method of measurement: Using radiography, the decrease in the width of the lesion is reported in percent.;The success and survival of the implant. Timepoint: 6 months after the surgery. Method of measurement: Using Implant Health scale (IHS) which ranges from 1 to 4. Score 1 means "complete health" of implant and includes no presence of pain and tenderness in function, no mobility, no secretion of exudate, and the reduction of bone height is less than 2 millimeters. Score 2 means "satisfying survival" of implant and includes no presence of pain and tenderness in function, no mobility, no secretion of exudate, and the reduction of bone height is 2-4 millimeters. Score 3 means "compromised survival" of implant and includes the possible presence of pain and tenderness in function, no mobility, possible secretion of exudate, the reduction of bone height is more than 4 millimeters or less than half of the implant's length, and probing depth is more than 7 millimeters. Score 4 means "complete failure" of implant and includes the presence of pain and tenderness in function, mobility, uncontrollable se | — |
Secondary
| Measure | Time frame |
|---|---|
| The esthetic of gingiva in the mid-buccal of the implant. Timepoint: Immediately after the surgery, 1 month after the surgery, 3 months after the surgery, 6 months after the surgery. Method of measurement: Using Gingival Esthetic Index in the mid buccal which evaluates the difference of implant's buccal margin with adjacent tooth margin and ranges from 0-4. 0 means no difference, 1 means difference less than 1 millimeter, 2 means difference of 1- 2 millimeters, 3 means difference of 2-3 millimeters, and 4 means difference more than 3 millimeters.;The esthetic of gingiva in the mesial and distal of the implant. Timepoint: Immediately after the surgery, 1 month after the surgery, 3 months after the surgery, 6 months after the surgery. Method of measurement: Using Gingival Esthetic Index in the mesial and distal of the implant which evaluates the height of the interdental papilla and ranges from 0-4. 0 means no presence of the papilla, 1 means the papilla's height is less than half of the gingival embrasure, 2 means the papilla's height is more than half of the gingival embrasure, 3 means complete growth of papilla into the interproximal space and 4 means the growth of papilla is over the interproximal space.;Crestal bone level. Timepoint: Immediately after the surgery, 3 months after the surgery, 6 months after the surgery. Method of measurement: Using radiography, the distance of crestal bone from the implant is reported in millimeter.;Plaque Index. Timepoint: Immediately after the surgery, 1 month after the surgery, 3 months after the surgery, 6 months after the surgery. Method of measurement: Using the O'Leary method. The patient is given a Fuschion tablet. The presence or absence of the stained deposites on the buccal, lingual, mesial, and distal surfaces is recorded and reported as the percent of stained surfaces to total surfaces.;Bleeding index. Timepoint: Immediately after the surgery, 1 month after the surgery, 3 months after the surgery, 6 months after the s | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Zohary
Rasht University of Medical Sciences
Outcome results
None listed