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Effect of midazolam ,ondansetron and their combination on post strabismus surgery nausea-vomiting

Comparing the effect of midazolam ,ondansetron and their combination on post strabismus surgery nausea-vomiting prevention

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20180416039326N8
Enrollment
160
Registered
2019-08-08
Start date
2019-08-23
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strabistmus. Unspecified strabismus

Interventions

Intervention 1: Intervention group 1: The patients in the group one receive 0.75mg/kg intravenous midazolam after the beginning of the anesthesia . Intervention 2: Intervention group 2: Patients in gr

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 62 Years

Inclusion criteria

Inclusion criteria: ASA I-II Candidate for strabismus surgery Age between 18-62 years The desire to participate in the study

Exclusion criteria

Exclusion criteria: Patient with motion sickness disease Receiving an anti-emetic drug in the last 24 hours Patient being treated with opioid Pregnant women smokers

Design outcomes

Primary

MeasureTime frame
Intensity and frequency of nausea and vomiting. Timepoint: 0-2 and 2-24 hours after surgery. Method of measurement: Calculating nausea-vomiting frequency by questionnaire and nausea-vomiting intensity by Visual Analogue Scale.

Secondary

MeasureTime frame
Pain frequency. Timepoint: 1)First 0-2 hours 2) first 2-24 hours. Method of measurement: questionnaire.;Pain intensity. Timepoint: 1)first 0-2 hours 2)first 2-24 hours. Method of measurement: Visual analogue scale.;Time of extubation. Timepoint: After the end of the surgery. Method of measurement: A Period between end of the surgery and extubation measured By anesthesiologist.;Recovery time. Timepoint: After the end of the surgery. Method of measurement: A period between the end of the surgery and going to the ward that is measured by modified aldrete score.;Patient satisfaction. Timepoint: At the time of the patient discharge. Method of measurement: Likert scale.;Time of eating and drinking. Timepoint: After the end of the surgery. Method of measurement: The first time of eating and drinking After the surgery.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza Shetabi

Esfahan University of Medical Sciences

Hamidshetabi@med.mui.ac.ir+98 31 3668 8138

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026