Condition 1: Ocular pain. Condition 2: Nausea and vomiting. Condition 3: cough. Condition 4: Sore throat. Condition 5: Extubation time. Ocular pain Nausea and vomiting Cough Acute pharyngitis
Conditions
Interventions
Intervention 1: Intervention Group: IV Lidocaine, Drug: Lidocaine 2% (20 mg/mL), Dose and Calculation Method: 1.5 mg/kg of patient body weight, Dose Cap: The maximum allowable dose is 100 mg, Injectio
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age range between 60 and 80 years Candidate for eye surgeries under general anesthesia Patient's informed consent to participate in the study ASA Class I-II
Exclusion criteria
Exclusion criteria: Having a history of allergies or known allergies to lidocaine, dexamethasone or other drugs used in the study protocol. Patients with a history of nausea and vomiting after surgery Taking strong painkillers (such as narcotics), anti-inflammatory drugs or corticosteroids or anti-nausea and vomiting before surgery. Existence of severe cognitive impairment (for example, advanced dementia), severe mental illness or lack of fluency in Persian, which makes it impossible to communicate and evaluate the criteria of outcomes (such as pain). Severe heart failure (less than 30% cardiac discharge fraction) Severe cardiac conduction disorders (such as second or third degree heart blocks) Severe liver failure (Cirrhosis of Child-P Class B or C) Severe renal failure (EGFR < 30 ml / min) Diseases neuromuscular (such as myasthenia gravis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extubation time. Timepoint: From the time the anesthetic agent (isoflurane) is discontinued until the moment the tracheal tube is removed (Extubation). Method of measurement: In minutes. Measurement method: Time recorded by stopwatch by a blinded assessor who was unaware of the patient's grouping.;Postoperative Pain Intensity. Timepoint: Every 10 minutes during the patient's stay in recovery. Method of measurement: Using a Visual Analog Scale (VAS) from 0 (no pain) to 10 (the most severe pain possible). | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Nausea and Vomiting (PONV). Timepoint: Every 10 minutes during the patient's stay in recovery. Method of measurement: Observational recording by the recovery ward nurse (blinded) and direct questioning of the patient.;Rescue analgesic use. Timepoint: Every 10 minutes during the patient's stay in recovery. Method of measurement: Direct questioning of the patient.;Rescue antiemetic use. Timepoint: Every 10 minutes during the patient's stay in recovery. Method of measurement: Observing and questioning the patient.;Length of stay in the recovery ward. Timepoint: Every 10 minutes during the patient's stay in recovery. Method of measurement: From the patient's entry into the recovery ward until they meet the criteria for discharge from recovery (Aldrete score = 9).;The patient's overall satisfaction with the quality of the recovery period after anesthesia. Timepoint: At the end of their recovery stay. Method of measurement: Using a Likert scale (from 1 "very dissatisfied" to 5 "very satisfied").;Drug-related side effects. Timepoint: Every 10 minutes during the patient's stay in recovery. Method of measurement: Observing and questioning the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Shetabi
Esfahan University of Medical Sciences
Outcome results
None listed