The preventive effect of intranasal dexamethasone on reducing postoperative nausea and vomiting after laparoscopic surgery in children.. Nausea and vomiting
Conditions
Interventions
Intervention 1: Intervention:children receive dexamethasone at a dose of 0.15 mg/kg after the induction of anesthesia. Intervention 2: Control group: Patients in the control group will receive normal
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 15 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for the Study:1. Age range between 2 to 15 years2. Candidates for laparoscopic herniorrhaphy and varicocele surgery (the type of surgery must be limited to these cases, and GI surgeries should be excluded)3. Informed consent from the patient's parents for participation in the study4. ASA classification I and II
Exclusion criteria
Exclusion criteria: Exclusion Criteria:1. Change in surgical method or anesthesia technique2. Requirement to keep the nasogastric tube in place after surgery3. Surgery duration exceeding two hours Exclusion Criteria [considering nasal mucosal disorders such as allergies and polyps]:**1. Patients with motion sickness2. Patients with a history of nausea and vomiting after surgery3. Nasal mucosal disorders such as allergies and polyps4. Patients who have received anti-nausea medications such as phenothiazines, scopolamine, corticosteroids, and tricyclic antidepressants within 24 hours prior to the surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary consequence of the occurrence of PONV (Postoperative Nausea and Vomiting) will be within the first 24 hours after surgery. Timepoint: The level of nausea will be assessed during the time spent in recovery, as well as when the patient is in the treatment units. The frequency of assessment will follow a pattern of every 15 minutes in the recovery unit and every four hours for the first 24 hours post-surgery. Method of measurement: The data obtained from this study will be analyzed using SPSS v28 and will be examined for descriptive statistics. Quantitative data will be reported with mean and standard deviation, while qualitative data will be reported with frequency and percentage. Additionally, to assess the significance of the impact on reducing nausea and vomiting, independent t-tests (for comparing continuous quantitative variables between two groups), Mann-Whitney tests (for comparing discrete quantitative variables between two groups), and chi-square tests (for comparing qualitative variables between two groups) will be employed. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Shetabi
Esfahan University of Medical Sciences
Outcome results
None listed