The effect of three different doses of intranasal dexamethasone in preventing sore throat after surgery in patients under general anesthesia

Investigating the effect of three different doses of intranasal dexamethasone in preventing sore throat after surgery in patients under general anesthesia

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20180416039326N23

Enrollment

100

Registered

2023-07-27

Start date

2023-08-05

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sore throat. Other specified complications of surgical and medical care, not elsewhere classified

Interventions

Intervention 1: Intervention group: After receiving 5 ml / kg of ringer lactate and pre-oxygenation for patients, the same anesthetic induction was performed including Fentanyl 2mcg / kg, Thiopental

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASAI-II Age between 18-65 Candidates for general surgery under anesthesia Completion of informed consent to participate in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sore throat. Timepoint: In recovery (every half hour) and in the ward (at zero hours, 2, 6, 12, and 24). Method of measurement: Scoring system for sore throat,cough and hoarseness.;Hoarseness. Timepoint: In recovery (every half hour) and in the ward (at zero hours, 2, 6, 12, and 24). Method of measurement: Scoring system for sore throat,cough and hoarseness.;Cough. Timepoint: In recovery (every half hour) and in the ward (at zero hours, 2, 6, 12, and 24). Method of measurement: Scoring system for sore throat,cough and hoarseness.;Score of pain. Timepoint: In recovery (every half hour) and in the ward (at zero hours, 2, 6, 12, and 24). Method of measurement: Visual Analogue Scale.;Total dose of analgesic. Timepoint: In the first 24 hours after the operation. Method of measurement: It is recorded in the data collection form.;Extubation time. Timepoint: After Extubation. Method of measurement: Clock.;Length of stay in recovery. Timepoint: After exiting recovery. Method of measurement: Clock.;Patient satisfaction score. Timepoint: At the end of 24 hours. Method of measurement: Likert scale.;Beginning time of using liquid foods. Timepoint: After using liquid foods. Method of measurement: Clock.;Beginning time of using solid foods. Timepoint: After using solid foods. Method of measurement: Clock.	—

Measure

Time frame

Sore throat. Timepoint: In recovery (every half hour) and in the ward (at zero hours, 2, 6, 12, and 24). Method of measurement: Scoring system for sore throat,cough and hoarseness.;Hoarseness. Timepoint: In recovery (every half hour) and in the ward (at zero hours, 2, 6, 12, and 24). Method of measurement: Scoring system for sore throat,cough and hoarseness.;Cough. Timepoint: In recovery (every half hour) and in the ward (at zero hours, 2, 6, 12, and 24). Method of measurement: Scoring system for sore throat,cough and hoarseness.;Score of pain. Timepoint: In recovery (every half hour) and in the ward (at zero hours, 2, 6, 12, and 24). Method of measurement: Visual Analogue Scale.;Total dose of analgesic. Timepoint: In the first 24 hours after the operation. Method of measurement: It is recorded in the data collection form.;Extubation time. Timepoint: After Extubation. Method of measurement: Clock.;Length of stay in recovery. Timepoint: After exiting recovery. Method of measurement: Clock.;Patient satisfaction score. Timepoint: At the end of 24 hours. Method of measurement: Likert scale.;Beginning time of using liquid foods. Timepoint: After using liquid foods. Method of measurement: Clock.;Beginning time of using solid foods. Timepoint: After using solid foods. Method of measurement: Clock.

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Countries

Iran (Islamic Republic of)

Contacts

Public Contacthamidreza shetabi

Esfahan University of Medical Sciences

hamidshetabi@med.mui.ac.ir+98 31 3445 2034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026